Skip page header and navigation

Staffing 100 North America

The Staffing 100 North America list celebrates the remarkable leaders whose influence and accomplishments elevate the workforce solutions ecosystem and take the industry forward.  

2025 Staffing 100 North America

Melissa Byington

CEO | Syncx; Quest Locum Tenens

Honoree profile

Since joining the industry in 1997, Melissa Byington has helped shape the healthcare staffing landscape with her strategic vision and business acumen. She serves as CEO of two independent companies —Syncx and Quest Locum Tenens — and is co-founder and board member of Era Locums. Under her leadership, Syncx revenue surged 229% to a projected $162 million in 2024 from $49.3 million in 2022. Strategies she implemented significantly improved client satisfaction, leading to an NPS score of +71.7 in 2024 from -34.5 the year prior. Meanwhile, Era Locums is projected to grow more than 200% in 2024 from 2023.